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Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma

The molecular mechanisms underlying the pathophysiology of Alzheimer's disease (AD) are still not fully understood. In AD, Wnt/beta-catenin signaling has been shown to be downregulated while the peroxisome proliferator-activated receptor (PPAR) gamma (mARN and protein) is upregulated. Certain n...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Vallée, Alexandre, Lecarpentier, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069291/
https://ncbi.nlm.nih.gov/pubmed/27807401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00459
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