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Glycogen Synthase Kinase 3β Inhibition Reduces Mitochondrial Oxidative Stress in Chronic Myocardial Ischemia
OBJECTIVES: Glycogen synthase kinase 3β (GSK-3β) inhibition has been found to increase microvascular density and improve myocardial blood flow in a porcine model of chronic myocardial ischemia and metabolic syndrome. Inhibition of GSK-3β can also be cardio protective by modulating fibrosis signaling...
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| Publicado no: | J Thorac Cardiovasc Surg |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5960424/ https://ncbi.nlm.nih.gov/pubmed/29523407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2017.12.127 |
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