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Tertiary structure of apolipoprotein A-I in nascent high-density lipoproteins

Understanding the function of high-density lipoprotein (HDL) requires detailed knowledge of the structure of its primary protein, apolipoprotein A-I (APOA1). However, APOA1 flexibility and HDL heterogeneity have confounded decades of efforts to determine high-resolution structures and consistent mod...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pourmousa, Mohsen, Song, Hyun D., He, Yi, Heinecke, Jay W., Segrest, Jere P., Pastor, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960303/
https://ncbi.nlm.nih.gov/pubmed/29712830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721181115
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