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Thermal Stability of Apolipoprotein A-I in High-Density Lipoproteins by Molecular Dynamics

Apolipoprotein (apo) A-I is an unusually flexible protein whose lipid-associated structure is poorly understood. Thermal denaturation, which is used to measure the global helix stability of high-density lipoprotein (HDL)-associated apoA-I, provides no information about local helix stability. Here we...

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Detalhes bibliográficos
Main Authors: Jones, Martin K., Catte, Andrea, Patterson, James C., Gu, Feifei, Chen, Jianguo, Li, Ling, Segrest, Jere P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716522/
https://ncbi.nlm.nih.gov/pubmed/19167289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.09.041
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