Revealing the specificity of regulatory T cells in murine autoimmune diabetes

Regulatory T cells (Tregs) control organ-specific autoimmunity in a tissue antigen-specific manner, yet little is known about their specificity in a natural repertoire. In this study, we used the nonobese diabetic (NOD) mouse model of autoimmune diabetes to investigate the antigen specificity of Tre...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Spence, Allyson, Purtha, Whitney, Tam, Janice, Dong, Shen, Kim, Youmin, Ju, Chia-Hsin, Sterling, Teague, Nakayama, Maki, Robinson, William H., Bluestone, Jeffrey A., Anderson, Mark S., Tang, Qizhi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960284/
https://ncbi.nlm.nih.gov/pubmed/29712852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715590115
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