In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes

The low number of CD4(+) CD25(+) regulatory T cells (T(regs)), their anergic phenotype, and diverse antigen specificity present major challenges to harnessing this potent tolerogenic population to treat autoimmunity and transplant rejection. In this study, we describe a robust method to expand antig...

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Autors principals: Tang, Qizhi, Henriksen, Kammi J., Bi, Mingying, Finger, Erik B., Szot, Greg, Ye, Jianqin, Masteller, Emma L., McDevitt, Hugh, Bonyhadi, Mark, Bluestone, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211775/
https://ncbi.nlm.nih.gov/pubmed/15184499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040139
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