Postnatal relative adrenal insufficiency results in methylation of the glucocorticoid receptor gene in preterm infants: a retrospective cohort study

BACKGROUND: To investigate the relationship between early-life stress and glucocorticoid receptor (GR) gene methylation, which may result in long-lasting neurodevelopmental impairment, we performed a longitudinal analysis of the methylation ratio within the GR gene promoter 1F region using next-gene...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Kantake, Masato, Ohkawa, Natsuki, Iwasaki, Tomohiro, Ikeda, Naho, Awaji, Atsuko, Saito, Nobutomo, Shoji, Hiromichi, Shimizu, Toshiaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960186/
https://ncbi.nlm.nih.gov/pubmed/29796117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0497-9
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