Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke

BACKGROUND: Activation of transforming growth factor-β-activated kinase 1 (TAK1) occurs after stroke and leads to an exacerbation of brain injury. TAK1 is involved in innate and adaptive immune responses, but it has divergent inflammatory effects that are dependent on the cell type in which it is ac...

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Gepubliceerd in:J Neuroinflammation
Hoofdauteurs: Chauhan, Anjali, Hudobenko, Jacob, Al Mamun, Abdullah, Koellhoffer, Edward C., Patrizz, Anthony, Ritzel, Rodney M., Ganesh, Bhanu P., McCullough, Louise D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960093/
https://ncbi.nlm.nih.gov/pubmed/29776451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1188-3
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