Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke

BACKGROUND: Activation of transforming growth factor-β-activated kinase 1 (TAK1) occurs after stroke and leads to an exacerbation of brain injury. TAK1 is involved in innate and adaptive immune responses, but it has divergent inflammatory effects that are dependent on the cell type in which it is ac...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Chauhan, Anjali, Hudobenko, Jacob, Al Mamun, Abdullah, Koellhoffer, Edward C., Patrizz, Anthony, Ritzel, Rodney M., Ganesh, Bhanu P., McCullough, Louise D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960093/
https://ncbi.nlm.nih.gov/pubmed/29776451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1188-3
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge