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Age-dependent susceptibility to reovirus encephalitis in mice is influenced by maturation of the type-I interferon response
BACKGROUND: Infants and young children are particularly susceptible to viral encephalitis, but the mechanisms are unknown. We determined the age-dependent contribution of innate and adaptive immune functions to reovirus-induced encephalitis in mice. METHODS: Newborn wild-type mice, 2 to 20 days of a...
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| Publicado en: | Pediatr Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5959747/ https://ncbi.nlm.nih.gov/pubmed/29364865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2018.13 |
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