Human apolipoprotein E genotype differentially affects olfactory behavior and sensory physiology in mice

Apolipoprotein E (ApoE) is an important lipid carrier in both the periphery and the brain. The ApoE ε4 allele (ApoE4) is the single most important genetic risk-factor for Alzheimer’s disease (AD) while the ε2 allele (ApoE2) is associated with a lower risk of AD-related neurodegeneration compared to...

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Udgivet i:Neuroscience
Main Authors: East, Brett S., Fleming, Gloria, Peng, Kathy, Olofsson, Jonas K., Levy, Efrat, Mathews, Paul M., Wilson, Donald A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959295/
https://ncbi.nlm.nih.gov/pubmed/29678753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.04.009
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