Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression

Although peroxisome proliferator-activated receptor-γ (PPARγ) coactivator 1α (PGC-1α) is a well-established transcriptional coactivator for the metabolic adaptation of mammalian cells to diverse physiological stresses, the molecular mechanism by which it functions is incompletely understood. Here we...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Cho, Hana, Rambout, Xavier, Gleghorn, Michael L., Nguyen, Phuong Quoc Thuc, Phipps, Christopher R., Miyoshi, Keita, Myers, Jason R., Kataoka, Naoyuki, Fasan, Rudi, Maquat, Lynne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959238/
https://ncbi.nlm.nih.gov/pubmed/29654059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.309773.117
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