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Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!

Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power, increased variance and the play of chance. Reliance on such analyses is likely to be more erroneous, and hence harmful, than applicati...

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Detalhes bibliográficos
Publicado no:Curr Control Trials Cardiovasc Med
Autor principal: Sleight, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59592/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11714402/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/cvm-1-1-025
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