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Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!
Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power, increased variance and the play of chance. Reliance on such analyses is likely to be more erroneous, and hence harmful, than applicati...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC59592/ https://ncbi.nlm.nih.gov/pubmed/11714402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cvm-1-1-025 |
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