Pioglitazone, a PPARγ agonist, reduces nicotine craving in humans, with marginal effects on abuse potential

Possibly through their actions upon glia, peroxisome proliferator-activated receptor agonists (PPAR) have been shown to alter the abuse potential of addictive drugs in several preclinical models. The current study extends this research into the human laboratory as the first clinical study into the e...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Jones, Jermaine D., Comer, Sandra D., Metz, Verena E., Manubay, Jeanne M., Mogali, Shanthi, Ciccocioppo, Roberto, Martinez, Suky, Mumtaz, Mudassir, Bisaga, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959043/
https://ncbi.nlm.nih.gov/pubmed/29020601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2017.10.002
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