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Oct4 suppresses IR-induced premature senescence in breast cancer cells through STAT3- and NF-κB-mediated IL-24 production

Breast cancer stem cells (BCSCs) are a small subpopulation of breast cancer cells that have been proposed to be a primary cause of failure of therapies, including ionizing radiation (IR). Their embryonic stem-like signature is associated with poor clinical outcome. In the present study, the function...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Kim, Jeong-Yub, Kim, Jeong-Chul, Lee, Ji-Yun, Park, Myung-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958730/
https://ncbi.nlm.nih.gov/pubmed/29749438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4391
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