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β C–H di-halogenation via iterative hydrogen atom transfer

A radical relay strategy for mono- and di-halogenation (iodination, bromination, and chlorination) of sp(3) C–H bonds has been developed. This first example of β C–H di-halogenation is achieved through sequential C–H abstraction by iterative, hydrogen atom transfer (HAT). A double C–H functionalizat...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Wappes, Ethan A., Vanitcha, Avassaya, Nagib, David A.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958344/
https://ncbi.nlm.nih.gov/pubmed/29896392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01214h
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