IgG-single-chain TRAIL fusion proteins for tumour therapy

Single-chain formats of TNF-related apoptosis inducing ligand (scTRAIL) can serve as effector components of tumour-associated antigen-targeted as well as non-targeted fusion proteins, being characterized by high tumour cell-specific induction of apoptosis through death receptor activation. We studie...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Siegemund, Martin, Schneider, Felix, Hutt, Meike, Seifert, Oliver, Müller, Ines, Kulms, Dagmar, Pfizenmaier, Klaus, Kontermann, Roland E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958125/
https://ncbi.nlm.nih.gov/pubmed/29773864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24450-8
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