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IgG-single-chain TRAIL fusion proteins for tumour therapy

Single-chain formats of TNF-related apoptosis inducing ligand (scTRAIL) can serve as effector components of tumour-associated antigen-targeted as well as non-targeted fusion proteins, being characterized by high tumour cell-specific induction of apoptosis through death receptor activation. We studie...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Siegemund, Martin, Schneider, Felix, Hutt, Meike, Seifert, Oliver, Müller, Ines, Kulms, Dagmar, Pfizenmaier, Klaus, Kontermann, Roland E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958125/
https://ncbi.nlm.nih.gov/pubmed/29773864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24450-8
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