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Proteins Breaking Bad: A Free Energy Perspective

Protein ageing may manifest as a mechanical disease that compromises tissue elasticity. As proved recently, while proteins respond to changes in force with an instantaneous elastic recoil followed by a folding contraction, aged proteins break bad, becoming unstructured polymers. Here, we explain thi...

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Detalhes bibliográficos
Publicado no:J Phys Chem Lett
Main Authors: Valle-Orero, Jessica, Tapia-Rojo, Rafael, Eckels, Edward C., Rivas-Pardo, Jaime Andres, Popa, Ionel, Fernández, Julio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957541/
https://ncbi.nlm.nih.gov/pubmed/28723106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.7b01509
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