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A HaloTag Anchored Ruler for Week-Long Studies of Protein Dynamics

Under physiological conditions, protein oxidation and misfolding occur with very low probability and on long times scales. Single molecule techniques provide the ability to distinguish between properly folded and damaged proteins that are otherwise masked in ensemble measurements. However, at physio...

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Dettagli Bibliografici
Pubblicato in:J Am Chem Soc
Autori principali: Popa, Ionel, Rivas-Pardo, Jaime Andrés, Eckels, Edward C., Echelman, Daniel J., Badilla, Carmen L., Valle-Orero, Jessica, Fernández, Julio M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510598/
https://ncbi.nlm.nih.gov/pubmed/27409974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05429
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