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A HaloTag Anchored Ruler for Week-Long Studies of Protein Dynamics

Under physiological conditions, protein oxidation and misfolding occur with very low probability and on long times scales. Single molecule techniques provide the ability to distinguish between properly folded and damaged proteins that are otherwise masked in ensemble measurements. However, at physio...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Popa, Ionel, Rivas-Pardo, Jaime Andrés, Eckels, Edward C., Echelman, Daniel J., Badilla, Carmen L., Valle-Orero, Jessica, Fernández, Julio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510598/
https://ncbi.nlm.nih.gov/pubmed/27409974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05429
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