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The work of titin protein folding as a major driver in muscle contraction

Single molecule atomic force microscopy and magnetic tweezers experiments have demonstrated that titin Ig domains are capable of folding against a pulling force, generating mechanical work which exceeds that produced by a myosin motor. We hypothesize that upon muscle activation, formation of actomyo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Annu Rev Physiol
Päätekijät: Eckels, Edward C., Tapia-Rojo, Rafael, Rivas-Pardo, Jamie Andrés, Fernández, Julio M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957538/
https://ncbi.nlm.nih.gov/pubmed/29433413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021317-121254
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