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The work of titin protein folding as a major driver in muscle contraction
Single molecule atomic force microscopy and magnetic tweezers experiments have demonstrated that titin Ig domains are capable of folding against a pulling force, generating mechanical work which exceeds that produced by a myosin motor. We hypothesize that upon muscle activation, formation of actomyo...
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| Yayımlandı: | Annu Rev Physiol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5957538/ https://ncbi.nlm.nih.gov/pubmed/29433413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021317-121254 |
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