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Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples

Nucleic acid material of adequate quality is crucial for successful high-throughput sequencing (HTS) analysis. DNA and RNA isolated from archival FFPE material are frequently degraded and not readily amplifiable due to chemical damage introduced during fixation. To identify optimal nucleic acid extr...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Kresse, Stine H., Namløs, Heidi M., Lorenz, Susanne, Berner, Jeanne-Marie, Myklebost, Ola, Bjerkehagen, Bodil, Meza-Zepeda, Leonardo A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957415/
https://ncbi.nlm.nih.gov/pubmed/29771965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197456
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