Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)(2)D(3)

BACKGROUND: The 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) together with parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) regulates calcium (Ca(2+)) and phosphate (Pi) homeostasis, 1,25(OH)(2)D(3) synthesis is mediated by hydroxylases of the cytochrome P450 (Cyp) family. Vitamin D...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kägi, Larissa, Bettoni, Carla, Pastor-Arroyo, Eva M., Schnitzbauer, Udo, Hernando, Nati, Wagner, Carsten A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957386/
https://ncbi.nlm.nih.gov/pubmed/29771914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195427
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