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Hypoxia Inducible Factors Modulate Mitochondrial Oxygen Consumption and Transcriptional Regulation of Nuclear-Encoded Electron Transport Chain Genes

Hypoxia inducible factor-1 (HIF1) is a stress-responsive nuclear transcription factor that is activated with a decrease in oxygen availability. HIF1 regulates the expression of genes involved in a cell’s adaptation to hypoxic stress, including those with mitochondrial specific function. To gain a mo...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Hwang, Hye Jin, Lynn, Scott G., Vengellur, Ajith, Saini, Yogesh, Grier, Elizabeth A., Ferguson-Miller, Shelagh M., LaPres, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957085/
https://ncbi.nlm.nih.gov/pubmed/26030260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5012892
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