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Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis

Treatment for metastatic cancer is a great challenge throughout the world. Commonly, directed inhibition of extracellular matrix metalloproteinases (MMPs) secreted by cancer cells can reduce metastasis. Here, a novel nanoplatform (HPMC NPs) assembled from hyaluronic acid (HA)-paclitaxel (PTX) prodru...

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Vydáno v:Theranostics
Hlavní autoři: Lv, Yaqi, Zhao, Xiangmei, Zhu, Lidan, Li, Sijia, Xiao, Qingqing, He, Wei, Yin, Lifang
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957012/
https://ncbi.nlm.nih.gov/pubmed/29774078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.23209
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