Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis

Treatment for metastatic cancer is a great challenge throughout the world. Commonly, directed inhibition of extracellular matrix metalloproteinases (MMPs) secreted by cancer cells can reduce metastasis. Here, a novel nanoplatform (HPMC NPs) assembled from hyaluronic acid (HA)-paclitaxel (PTX) prodru...

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Bibliographic Details
Published in:Theranostics
Main Authors: Lv, Yaqi, Zhao, Xiangmei, Zhu, Lidan, Li, Sijia, Xiao, Qingqing, He, Wei, Yin, Lifang
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957012/
https://ncbi.nlm.nih.gov/pubmed/29774078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.23209
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