NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects

Failure of neural tube closure leads to neural tube defects (NTDs), which can have serious neurological consequences or be lethal. Use of antiepileptic drugs (AEDs) during pregnancy increases the incidence of NTDs in offspring by unknown mechanisms. Here we show that during Xenopus laevis neural tub...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Sequerra, Eduardo B., Goyal, Raman, Castro, Patricio A., Levin, Jacqueline B., Borodinsky, Laura N.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956989/
https://ncbi.nlm.nih.gov/pubmed/29712790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2634-17.2018
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