NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects

Failure of neural tube closure leads to neural tube defects (NTDs), which can have serious neurological consequences or be lethal. Use of antiepileptic drugs (AEDs) during pregnancy increases the incidence of NTDs in offspring by unknown mechanisms. Here we show that during Xenopus laevis neural tub...

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Vydáno v:J Neurosci
Hlavní autoři: Sequerra, Eduardo B., Goyal, Raman, Castro, Patricio A., Levin, Jacqueline B., Borodinsky, Laura N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956989/
https://ncbi.nlm.nih.gov/pubmed/29712790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2634-17.2018
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