The personalized Alzheimer's disease cortical thickness index predicts likely pathology and clinical progression in mild cognitive impairment

INTRODUCTION: An Alzheimer's disease (AD) biomarker adjusted for age-related brain changes should improve specificity for AD-related pathological burden. METHODS: We calculated a brain-age-adjusted “personalized AD cortical thickness index” (pADi) in mild cognitive impairment patients from the...

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Détails bibliographiques
Publié dans:Alzheimers Dement (Amst)
Auteurs principaux: Racine, Annie M., Brickhouse, Michael, Wolk, David A., Dickerson, Bradford C.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Special Section: State of the Field: Advances in Neuroimaging from the 2017 Alzheimer’s Imaging Consortium. (Guest Editors: Drs. David Wolk, Victor Villemagne & Bradford Dickerson)
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956936/
https://ncbi.nlm.nih.gov/pubmed/29780874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.02.007
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