Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios

INTRODUCTION: We tested the hypothesis that the amyloid β (Aβ) peptide ratios are more stable than Aβ(42) alone when biofluids are exposed to two preanalytical conditions known to modify measurable Aβ concentration. METHODS: Human cerebrospinal fluid (CSF) and culture media (CM) from human cortical...

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Detalles Bibliográficos
Publicado en:Alzheimers Dement (Amst)
Main Authors: Toombs, Jamie, Foiani, Martha S., Wellington, Henrietta, Paterson, Ross W., Arber, Charles, Heslegrave, Amanda, Lunn, Michael P., Schott, Jonathan M., Wray, Selina, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
Assuntos:
CSF Biomarkers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956932/
https://ncbi.nlm.nih.gov/pubmed/29780875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.02.005
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