Induced Cre-mediated knockdown of Brca1 in skeletal muscle reduces mitochondrial respiration and prevents glucose intolerance in adult mice on a high-fat diet

The breast cancer type 1 susceptibility protein (Brca1) is a regulator of DNA repair in mammary gland cells; however, recent cell culture evidence suggests that Brca1 influences other processes, including those in nonmammary cells. In this study, we sought to determine whether Brca1 is necessary for...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Jackson, Kathryn C., Tarpey, Michael D., Valencia, Ana P., Iñigo, Melissa R., Pratt, Stephen J., Patteson, Daniel J., McClung, Joseph M., Lovering, Richard M., Thomson, David M., Spangenburg, Espen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956240/
https://ncbi.nlm.nih.gov/pubmed/29401626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700464R
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados