Optimization to detect TP53 mutations in circulating cell-free tumor DNA from patients with serous epithelial ovarian cancer

OBJECTIVE: Circulating cell-free tumor DNA (cfDNA) is the DNA released by apoptotic and necrotic cells of the primary tumor into the blood during the period of tumor development. The cfDNA reflects the genetic and epigenetic alterations of the original tumor. TP53 mutations are a defining feature of...

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Détails bibliographiques
Publié dans:Obstet Gynecol Sci
Auteurs principaux: Park, Yu Ran, Kim, Yong-Man, Lee, Shin Wha, Lee, Ha Young, Lee, Gun Eui, Lee, Jong-Eun, Kim, Young-Tak
Format: Artigo
Langue:Inglês
Publié: Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 2018
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956115/
https://ncbi.nlm.nih.gov/pubmed/29780774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5468/ogs.2018.61.3.328
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