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Optical functionalization of human Class A orphan G-protein-coupled receptors

G-protein-coupled receptors (GPCRs) form the largest receptor family, relay environmental stimuli to changes in cell behavior and represent prime drug targets. Many GPCRs are classified as orphan receptors because of the limited knowledge on their ligands and coupling to cellular signaling machineri...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Morri, Maurizio, Sanchez-Romero, Inmaculada, Tichy, Alexandra-Madelaine, Kainrath, Stephanie, Gerrard, Elliot J., Hirschfeld, Priscila P., Schwarz, Jan, Janovjak, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956105/
https://ncbi.nlm.nih.gov/pubmed/29769519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04342-1
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