Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

The structural basis of the interaction between the CD4 coreceptor and a class II major histocompatibility complex (MHC) is described. The crystal structure of a complex containing the human CD4 N-terminal two-domain fragment and the murine I-A(k) class II MHC molecule with associated peptide (pMHCI...

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Bibliographic Details
Main Authors: Wang, Jia-huai, Meijers, Rob, Xiong, Yi, Liu, Jin-huan, Sakihama, Toshiko, Zhang, Rongguang, Joachimiak, Andrzej, Reinherz, Ellis L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC59561/
https://ncbi.nlm.nih.gov/pubmed/11535811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191124098
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