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Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width

Nutrition and metabolism are known to influence chromatin biology and epigenetics through post-translational modifications, yet how this interaction influences genomic architecture and connects to gene expression is unknown. Here we consider, as a model, the metabolically-driven dynamics of H3K4me3,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Dai, Ziwei, Mentch, Samantha J., Gao, Xia, Nichenametla, Sailendra N., Locasale, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955993/
https://ncbi.nlm.nih.gov/pubmed/29769529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04426-y
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