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Cattle with a precise, zygote-mediated deletion safely eliminate the major milk allergen beta-lactoglobulin
We applied precise zygote-mediated genome editing to eliminate beta-lactoglobulin (BLG), a major allergen in cows’ milk. To efficiently generate LGB knockout cows, biopsied embryos were screened to transfer only appropriately modified embryos. Transfer of 13 pre-selected embryos into surrogate cows...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955954/ https://ncbi.nlm.nih.gov/pubmed/29769555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25654-8 |
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