A Guinea Pig Cytomegalovirus Resistant to the DNA Maturation Inhibitor BDCRB

Herpesvirus DNA packaging is an essential step in virion morphogenesis and an important target for antiviral development. The halogenated benzimidazole 2-bromo-5,6-dichloro-1-β-d-ribofuranosyl-1H-benzimidazole (BDCRB) was the first compound found to selectively disrupt DNA packaging. It has activity...

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Publicado no:Antiviral Res
Main Authors: Ourahmane, Amine, Sauer, Anne, Nixon, Daniel E., Murphy, Christine, Mondello, Melissa, Douglass, Erin, Siegmund, Stephanie, Ben Wang, Jian, McVoy, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955856/
https://ncbi.nlm.nih.gov/pubmed/29649495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.04.006
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