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Dramatic Effects of 2-Bromo-5,6-Dichloro-1-β-d-Ribofuranosyl Benzimidazole Riboside on the Genome Structure, Packaging, and Egress of Guinea Pig Cytomegalovirus

The halogenated benzimidazoles BDCRB (2-bromo-5,6-dichloro-1-β-d-riborfuranosyl benzimidazole riboside) and TCRB (2,5,6-trichloro-1-β-d-riborfuranosyl benzimidazole riboside) were the first compounds shown to inhibit cleavage and packaging of herpesvirus genomes. Both inhibit the formation of unit l...

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Detalles Bibliográficos
Main Authors: Nixon, Daniel E., McVoy, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC369448/
https://ncbi.nlm.nih.gov/pubmed/14747528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1623-1635.2004
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