Crystal Structures of RMI1 and RMI2, Two OB-fold Regulatory Subunits of the BLM Complex

Mutations in BLM, a RecQ-like helicase, are linked to the autosomal recessive cancer-prone disorder Bloom's syndrome. BLM associates with Topoisomerase(Topo) IIIα, RMI1 and RMI2 to form the BLM complex that is essential for genome stability. The RMI1-RMI2 heterodimer stimulates the dissolution...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Wang, Feng, Yang, Yuting, Singh, Thiyam Ramsing, Busygina, Valeria, Guo, Rong, Wan, Ke, Wang, Weidong, Sung, Patrick, Meetei, Amom Ruhikanta, Lei, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955610/
https://ncbi.nlm.nih.gov/pubmed/20826342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.008
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