Interferon lambda is required for interferon gamma-expressing NK cell responses but does not afford antiviral protection during acute and persistent murine cytomegalovirus infection

Interferon lambda (IFNλ) is a group of cytokines that belong to the IL-10 family. They exhibit antiviral activities against certain viruses during infection of the liver and mucosal tissues. Here we report that IFNλ restricts in vitro replication of the β-herpesvirus murine cytomegalovirus (mCMV). H...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gimeno Brias, Silvia, Marsden, Morgan, Forbester, Jessica, Clement, Mathew, Brandt, Cordelia, Harcourt, Katherine, Kane, Leanne, Chapman, Lucy, Clare, Simon, Humphreys, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955543/
https://ncbi.nlm.nih.gov/pubmed/29768502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197596
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