Cargando...
High-dimensional single-cell phenotyping reveals extensive haploinsufficiency
Haploinsufficiency, a dominant phenotype caused by a heterozygous loss-of-function mutation, has been rarely observed. However, high-dimensional single-cell phenotyping of yeast morphological characteristics revealed haploinsufficiency phenotypes for more than half of 1,112 essential genes under opt...
Gardado en:
| Publicado en: | PLoS Biol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955526/ https://ncbi.nlm.nih.gov/pubmed/29768403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005130 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|