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Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Giardiasis is a common diarrheal disease caused by the protozoan parasite Giardia intestinalis. Cysteine proteases (CPs) are acknowledged as virulence factors in Giardia but their specific role in the molecular pathogenesis of disease is not known. Herein, we aimed to characterize the three main sec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Virulence
Hauptverfasser: Liu, Jingyi, Ma'ayeh, Showgy, Peirasmaki, Dimitra, Lundström-Stadelmann, Britta, Hellman, Lars, Svärd, Staffan G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955458/
https://ncbi.nlm.nih.gov/pubmed/29726306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2018.1451284
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