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Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Giardiasis is a common diarrheal disease caused by the protozoan parasite Giardia intestinalis. Cysteine proteases (CPs) are acknowledged as virulence factors in Giardia but their specific role in the molecular pathogenesis of disease is not known. Herein, we aimed to characterize the three main sec...

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Bibliografske podrobnosti
izdano v:Virulence
Main Authors: Liu, Jingyi, Ma'ayeh, Showgy, Peirasmaki, Dimitra, Lundström-Stadelmann, Britta, Hellman, Lars, Svärd, Staffan G.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955458/
https://ncbi.nlm.nih.gov/pubmed/29726306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2018.1451284
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