miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation

Although the oncogene MMSET (also known as NSD2 or WHSC1) has an essential role in malignancies, its impact on human endometrial cancer (EC) metastasis and the molecular mechanism of MMSET regulation are largely unknown. We report that MMSET was markedly upregulated in EC cell lines and EC tissues,...

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Vydáno v:Oncotarget
Hlavní autoři: Dong, Peixin, Xiong, Ying, Yue, Junming, Hanley, Sharon J.B., Watari, Hidemichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955424/
https://ncbi.nlm.nih.gov/pubmed/29796186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25298
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