Rare genetic heterogeneity within single tumor discovered for the first time in colorectal liver metastases after liver resection

Effective individualized treatment of patients with colorectal liver metastases (CLM) requires tumor genotyping, usually based on the analysis of one single sample per patient. Therapy failure may partially be explained by sampling errors and/or intratumoral genetic heterogeneity. We aimed to demons...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Sebagh, Mylène, Bosselut, Nelly, Santos, Alexandre Dos, Allard, Marc-Antoine, Ruiz, Aldrick, Saffroy, Raphaël, Cherqui, Daniel, Vibert, Eric, Castaing, Denis, Adam, René, Cunha, Antonio Sa, Lemoine, Antoinette
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955166/
https://ncbi.nlm.nih.gov/pubmed/29774112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25119
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