Rare genetic heterogeneity within single tumor discovered for the first time in colorectal liver metastases after liver resection

Effective individualized treatment of patients with colorectal liver metastases (CLM) requires tumor genotyping, usually based on the analysis of one single sample per patient. Therapy failure may partially be explained by sampling errors and/or intratumoral genetic heterogeneity. We aimed to demons...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sebagh, Mylène, Bosselut, Nelly, Santos, Alexandre Dos, Allard, Marc-Antoine, Ruiz, Aldrick, Saffroy, Raphaël, Cherqui, Daniel, Vibert, Eric, Castaing, Denis, Adam, René, Cunha, Antonio Sa, Lemoine, Antoinette
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955166/
https://ncbi.nlm.nih.gov/pubmed/29774112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25119
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