Loading...

Camptothecin induces G(2)/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen species

In the present study, we report that camptothecin (CPT) caused irreversible cell cycle arrest at the G(2)/M phase, and was associated with decreased levels of cell division cycle 25C (Cdc25C) and increased levels of cyclin B1, p21, and phospho-H3. Interestingly, the reactive oxygen species (ROS) inh...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Prasad Tharanga Jayasooriya, Rajapaksha Gedara, Dilshara, Matharage Gayani, Neelaka Molagoda, Ilandarage Menu, Park, Cheol, Park, Sang Rul, Lee, Seungheon, Choi, Yung Hyun, Kim, Gi-Young
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955160/
https://ncbi.nlm.nih.gov/pubmed/29774099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24934
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!