Targeting Tie-2/angiopoietin axis in experimental mesothelioma confers differential responses and raises predictive implications

Malignant pleural mesothelioma is resistant to currently used treatment. Angiopoieitn-1 directly promotes mesothelioma cell growth in a Tie-2-dependent fashion. Angiopoietin/Tie-2 axis may thus be valid targets for therapeutic interventions against mesothelioma. We hypothesized that a soluble angiop...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Magkouta, Sophia, Pappas, Apostolos, Pateras, Ioannis S., Kollintza, Androniki, Moschos, Charalampos, Vazakidou, Maria-Eleni, Karavana, Vasiliki, Gorgoulis, Vassilis G., Kalomenidis, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955153/
https://ncbi.nlm.nih.gov/pubmed/29774102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25004
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