The cyclin-dependent kinase inhibitor flavopiridol (alvocidib) inhibits metastasis of human osteosarcoma cells

Osteosarcoma is the most common primary malignant neoplasm of bone and typically occurs in children and young adults. As a highly metastatic malignancy, 15–20% of osteosarcoma patients are diagnosed after the tumor has already metastasized (typically to the lungs), which translates to 5-year surviva...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Zocchi, Loredana, Wu, Stephanie C., Wu, Jie, Hayama, Ken L., Benavente, Claudia A.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955096/
https://ncbi.nlm.nih.gov/pubmed/29805751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25239
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